Tab. FLUCONAL 50MG information and price in Bangladesh

Information: Tab. FLUCONAL 50MG

Therapeutic action – Antifungal Indications – Oesophageal candidiasis – Moderate to severe oropharyngeal candidiasis – Secondary prophylaxis of recurrent candidiasis in immunocompromised patients – Cryptococcocal meningitis, after treatment with amphotericin B + flucytosine or in combination with amphotericin B – Secondary prophylaxis of cryptococcocal infections Presentation – 50 mg, 100 mg and 200 mg capsules or tablets – 50 mg/5 ml oral solution Dosage and duration – Oesophageal candidiasis, oropharyngeal candidiasis, secondary prophylaxis of candidiasis Child over 1 week: 3 to 6 mg/kg once daily Adult: 50 to 200 mg once daily These doses may be increased up to 400 mg/day if necessary. The treatment lasts 14 to 21 days for oesophageal candidiasis; 7 to 14 days for oropharyngeal candidiasis; as long as required for secondary prophylaxis. – Cryptococcocal meningitis After treatment with amphotericin B + flucytosine Child > 1 week 6 to 12 mg/kg once daily (max. 800 mg/day) for 8 weeks Adult 400 to 800 mg once daily for 8 weeks or In combination with amphotericin B Child > 1 week 12 mg/kg once daily (max. 800 mg/day) for 2 weeks (with amphotericin B) then 6 to 12 mg/kg once daily for 8 weeks Adult 800 mg once daily for 2 weeks (with amphotericin B) then 400 to 800 mg once daily for 8 weeks – Secondary prophylaxis of cryptococcocal infections Child: 6 mg/kg once daily (max. 200 mg/day), as long as required Adult: 200 mg once daily, as long as required contra-indications, adverse effects, precautions – Administer with caution to patients with hepatic or renal impairment, cardiac disorders (bradycardia, heart rhythm disorders, etc.). Reduce the dose by half in patients with renal impairment. – May cause: gastrointestinal disturbances, headache, skin reactions sometimes severe, anaphylactic reactions; severe hepatic disorders, haematologic (leukopenia, thrombocytopenia) and cardiac disorders (QT-prolongation). Stop treatment in the event of anaphylactic reaction, hepatic disorders or severe skin reaction. – In the event of prolonged treatment, monitor hepatic function. – Do not administer simultaneously with rifampicin, administer 12 hours apart (rifampicin in the morning, fluconazole in the evening). – Avoid or monitor combination with: • drugs that prolong the QT interval (amiodarone, chloroquine, erythromycin, haloperidol, mefloquine, pentamidine, quinine); • warfarin, carbamazepine, phenytoin, rifabutin, benzodiazepines, calcium-channel blockers, certain antiretrovirals (e.g. nevirapine, saquinavir, zidovudine): increased blood concentration of these drugs. – Pregnancy and breast-feeding: to be used only in severe or life-threatening infections, particularly during the first trimester of pregnancy (risk of foetal malformations). Remarks – For cryptococcocal meningitis, when amphotericin B is not available or not tolerated, fluconazole may be administered alone: Child over 1 week: 12 mg/kg once daily (max. 1200 mg/d) for 2 weeks then, 12 mg/kg once daily (max. 800 mg/d) for 8 weeks Adult: 1200 mg once daily for 2 weeks then, 800 mg once daily for 8 weeks – For the treatment of histoplasmosis, fluconazole is less effective than itraconazole. It should be used (child: 10 to 12 mg/kg once daily, max. 400 mg/d ; adult: 400 mg on Day 1 then 200 to 400 mg once daily, for 6 to 12 weeks) only in patients unable to tolerate itraconazole. – For the treatment of dermatophytosis of the scalp, fluconazole may be used as a secondary option (child: 6 mg/kg once daily, max. 200 mg/d; adult: 200 mg once daily, for 2 to 4 weeks) but itraconazole is preferred for this indication. – For the treatment of genital candidiasis (vulvovaginitis, balanitis), fluconazole is only used if local treatment fails: 150 mg as a single dose in adults. – Storage: below 25°C – Once reconstituted, oral solution keeps for 2 weeks. http://www.acmeglobal.com/products/ https://medlineplus.gov/druginfo/meds/a690002.html https://en.wikipedia.org/wiki/Fluconazole

Caution: Tab. FLUCONAL 50MG

Before taking Tab. FLUCONAL 50MG, inform your doctor if you or your child have liver or kidney problems or any allergies. It should be used with caution in patients with liver problems due to alcohol to prevent the risk of liver damage.

Tab. FLUCONAL 50MG should be used with caution in pregnant women only if clearly advised by the doctor and can be used in breastfeeding women.

Tab. FLUCONAL 50MG is not recommended for use in children less than 10 years of age and should be used with caution in elderly patients.

Consult your doctor if you experience any side effects or unusual effects during treatment with Tab. FLUCONAL 50MG.

Safety: Tab. FLUCONAL 50MG

It is unsafe to consume alcohol with Tab. FLUCONAL 50MG